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[多发伤患者肝损伤的预后与治疗]

[Prognosis and therapy of liver injury in patients with multiple injuries].

作者信息

Varney M, Becker H, Röher H D

机构信息

Klinik für Allgemeine und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf.

出版信息

Chirurg. 1990 Oct;61(10):711-6.

PMID:2276301
Abstract

Between 1.7. 1986 and 31.10. 1989 abdominal trauma was seen in 108 (35.8%) of 300 polytraumatized patients, 44 of these showed rupture of the liver. 23 patients belonged to grade I-III (Moore-classification) and 11 patients to grade IV. Extensive bilobar parenchymal destruction (grade V) was found in 10 patients including 6 patients with retrohepatic vena cava injury. 80% of all patients with liver trauma had intraabdominally associated injuries. In Grade I-II (n = 4) patients were treated conservatively and continuously observed by ultrasound. Injuries graded to III (n = 19) and IV (n = 11) were mostly treated by simple suture or segmental resection. In grade V hemihepatectomy was done in 4 cases, in 2 cases combined by packing and in 1 patient packing only. In 3 patients no adequate therapy was possible. The mortality rate being 36% (n = 16), hemorrhagic complications were the most common cause of death (7 of 16 patients). This was due only to the patients graded to V. In comparison the prognostic factor in grade I-IV ruptures were the associated injuries. In all these cases hemorrhage was stopped by a conservative, organ-retaining therapy. No further hemorrhage occurred. Liver packing was mainly used as additional treatment in cases of coagulopathy after resection. Further indications are extensive bilobar parenchymal destruction without the possibility of primary reconstruction and temporary hemostasis to allow transport to a specialized hospital.

摘要

1986年7月1日至1989年10月31日期间,300例多发伤患者中有108例(35.8%)出现腹部创伤,其中44例肝脏破裂。23例患者属于Ⅰ-Ⅲ级(Moore分类),11例患者属于Ⅳ级。10例患者出现广泛的双叶实质破坏(Ⅴ级),其中6例伴有肝后腔静脉损伤。所有肝外伤患者中有80%伴有腹腔内其他损伤。Ⅰ-Ⅱ级(n = 4)患者采用保守治疗,并通过超声持续观察。Ⅲ级(n = 19)和Ⅳ级(n = 11)损伤大多采用单纯缝合或节段性切除治疗。Ⅴ级患者中,4例行半肝切除术,2例联合填塞,1例仅行填塞。3例患者无法进行充分治疗。死亡率为36%(n = 16),出血并发症是最常见的死亡原因(16例患者中有7例)。这仅归因于Ⅴ级患者。相比之下,Ⅰ-Ⅳ级破裂的预后因素是合并的其他损伤。在所有这些病例中,通过保守的保留器官治疗止住了出血,未再发生出血。肝填塞主要用于切除术后凝血功能障碍的病例作为辅助治疗。其他适应证包括广泛的双叶实质破坏而无法进行一期重建以及用于临时止血以便转运至专科医院。

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