Cretin B, Davanture C, Longato N, Philippi N, Blanc F
Pôle tête et cou, département de neurologie des hôpitaux universitaires de Strasbourg, CMRR d'Alsace, 1, avenue Molière, 67000 Strasbourg, France.
Rev Neurol (Paris). 2013 Jan;169(1):76-83. doi: 10.1016/j.neurol.2012.03.013. Epub 2012 Jul 2.
A chronic subjective cognitive impairment can be symptomatic of temporal lobe epilepsy (TLE); it is thereby frequently reversible with the use of antiepileptic monotherapy. In this field, two distinct syndromes have been described: the Epileptic Amnesic Syndrome (EAS) and the Syndrome of Transient Epileptic Amnesia. Their diagnostic criteria have much in common but identification of STEA is based only on transient amnesic attacks. On the contrary, EAS takes into account subtle temporal lobe seizures. Here, we report a case where chronic cognitive disturbances were combined with very limited temporal lobe seizures while amnesic attacks were lacking. Antiepileptic drug treatment led to normalization of cognitive function. The criteria of STEA were not applicable because of the lack of transient amnesia in the patients' medical history. Considering brief episodes of flashbacks and abdominal pain as possibly seizure-related, the criteria of EAS were more operative: they allowed proper investigation to confirm TLE in our patient.
慢性主观认知障碍可能是颞叶癫痫（TLE）的症状；因此，使用抗癫痫单药治疗通常可使其逆转。在该领域，已描述了两种不同的综合征：癫痫性失忆综合征（EAS）和短暂性癫痫性失忆综合征。它们的诊断标准有很多共同之处，但STEA的识别仅基于短暂性失忆发作。相反，EAS考虑了细微的颞叶癫痫发作。在此，我们报告一例病例，该病例存在慢性认知障碍，同时颞叶癫痫发作非常有限且无失忆发作。抗癫痫药物治疗使认知功能恢复正常。由于患者病史中缺乏短暂性失忆，STEA的标准不适用。考虑到短暂的闪回发作和腹痛可能与癫痫发作有关，EAS的标准更具操作性：它们使我们能够进行适当的检查以确诊患者的TLE。
