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[短暂性癫痫性遗忘症]

[Transient epileptic amnesia].

作者信息

Fouchard Audrey-Anne, Mondon Karl, De Toffol Bertrand

机构信息

CHU de Tours, service de neurologie, 37044 Tours cedex, France; Université François-Rabelais, 37032 Tours cedex 1, France.

CHU de Tours, centre de mémoire de ressources et recherches, France; Inserm U930, 37044 Tours cedex, France.

出版信息

Presse Med. 2017 Jan;46(1):31-35. doi: 10.1016/j.lpm.2016.11.004. Epub 2016 Dec 7.

DOI:10.1016/j.lpm.2016.11.004
PMID:27955802
Abstract

Transient epileptic amnesia (TEA) is a sub-type of mesial temporal lobe epilepsy, with amnesic seizures. TEA is characterized by recurrent episodes of amnesia. Diagnostic criteria are available for TEA, and these memory disturbances should not be misdiagnosed with transient global amnesia. The neuropsychological evaluation is normal, however, autobiographical memory impairment is present in 70% of the cases and accelerated long term forgetting in 44%. When a patient complains of memory disturbances, especially autobiographical memory, TEA must be considered especially if there was an amnesic episode and symptoms that suggest temporal epilepsia. Video electroencephalography monitoring of sleep is a precious diagnostic tool, as epileptiform activities are found during sleep in 83% cases. TEA is pharmaco-sensitive, with full treatment response in 73 to 96% of the cases.

摘要

短暂性癫痫性遗忘症(TEA)是内侧颞叶癫痫的一种亚型,伴有遗忘性发作。TEA的特征是反复出现遗忘发作。目前有TEA的诊断标准,这些记忆障碍不应与短暂性全面性遗忘症误诊。神经心理学评估正常,然而,70%的病例存在自传体记忆损害,44%的病例存在加速的长期遗忘。当患者主诉记忆障碍,尤其是自传体记忆时,必须考虑TEA,特别是如果有遗忘发作和提示颞叶癫痫的症状。睡眠视频脑电图监测是一种宝贵的诊断工具,因为83%的病例在睡眠期间可发现癫痫样活动。TEA对药物敏感,73%至96%的病例有完全的治疗反应。

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