使用荧光咪唑受体识别肌醇 1,4,5-三磷酸。
Recognition of myo-inositol 1,4,5-trisphosphate using a fluorescent imidazolium receptor.
机构信息
Department of Bioinspired Science (WCU), Ewha Womans University, Seoul 120-750, Korea.
出版信息
Chem Commun (Camb). 2012 Aug 18;48(64):7928-30. doi: 10.1039/c2cc33717g. Epub 2012 Jul 5.
PMID:22763433
Abstract
The first example of an imidazolium-based fluorescent receptor for D-myo-inositol 1,4,5-trisphosphate (IP(3)) is reported in this study. The fluorescent receptor 1 bearing four imidazolium and pyrene groups displayed a large fluorescent quenching effect with myo-IP(3) compared to fluorescent changes with various IP series, pyrophosphate, and ATP.
摘要
本研究报道了首例基于咪唑鎓的荧光 D-肌醇 1,4,5-三磷酸（IP（3））受体。与各种 IP 系列、焦磷酸盐和 ATP 的荧光变化相比，带有四个咪唑鎓和芘基团的荧光受体 1 与肌醇 1,4,5-三磷酸（IP（3））显示出较大的荧光猝灭效应。
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