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胸降主动脉和胸腹主动脉瘤腔内修复与开放手术修复后脊髓缺血。

Spinal cord ischemia after endovascular aortic repair versus open surgical repair for descending thoracic and thoracoabdominal aortic aneurism.

机构信息

Department of Anesthesiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.

出版信息

J Anesth. 2012 Dec;26(6):805-11. doi: 10.1007/s00540-012-1434-2. Epub 2012 Jul 5.

DOI:10.1007/s00540-012-1434-2
PMID:22763469
Abstract

PURPOSE

Thoracic endovascular aortic repair (TEVAR) an emerging less invasive alternative to surgery, is now being increasingly employed, but spinal cord ischemia (SCI) is still a threat with this procedure. Delayed paraplegia has been frequently observed after TEVAR, suggesting there may be different courses of SCI between TEVAR and the conventional open surgical repair (OSR) of thoracic and thoracoabdominal aneurysms. Therefore, we conducted a study to investigate the risk factors for and the course of SCI after TEVAR and OSR.

METHODS

We studied a series of 414 OSR and 94 TEVAR patients prospectively. Postoperative motor function, sensory disturbance, and bladder disturbance were assessed daily to evaluate the course of SCI. Previously reported risk factors for SCI were investigated.

RESULTS

Spinal cord ischemia occurred in 6 patients (6.4 %) in the TEVAR group, and in 18 patients (4.3 %) in the OSR group, resulting in no significant difference (p = 0.401). A greater percentage of patients (n = 4, 66.7 %) with SCI in the TEVAR group had a delayed onset, compared with 16.7 % (n = 3) in the OSR group (p = 0.038). The rate of recovery of walking function after SCI and the incidence of sensory disturbance and bladder dysfunction was similar in the two groups. Multivariate analysis demonstrated that, in the TEVAR group, the stent length of aortic coverage was a significant risk factor for SCI.

CONCLUSION

The incidence of SCI was similar in the OSR and TEVAR groups, but delayed SCI occurred more frequently in the TEVAR group. Except for the delayed onset of SCI, SCI showed a similar course of recovery in the two groups.

摘要

目的

胸主动脉腔内修复术(TEVAR)作为一种新兴的微创替代手术方法,目前应用越来越广泛,但脊髓缺血(SCI)仍然是该手术的威胁。TEVAR 后常观察到迟发性截瘫,这表明 TEVAR 与胸主动脉和胸腹主动脉瘤的传统开放手术修复(OSR)之间可能存在不同的 SCI 病程。因此,我们进行了一项研究,以调查 TEVAR 和 OSR 后 SCI 的危险因素和病程。

方法

我们前瞻性研究了 414 例 OSR 和 94 例 TEVAR 患者。术后每天评估运动功能、感觉障碍和膀胱障碍,以评估 SCI 的病程。研究了先前报道的 SCI 危险因素。

结果

TEVAR 组 6 例(6.4%)和 OSR 组 18 例(4.3%)发生脊髓缺血,差异无统计学意义(p=0.401)。TEVAR 组发生 SCI 的患者中,更多的患者(n=4,66.7%)发病延迟,而 OSR 组为 16.7%(n=3)(p=0.038)。两组 SCI 后行走功能恢复率、感觉障碍和膀胱功能障碍发生率相似。多因素分析表明,在 TEVAR 组中,主动脉覆盖支架长度是 SCI 的一个显著危险因素。

结论

OSR 和 TEVAR 组的 SCI 发生率相似,但 TEVAR 组更常发生迟发性 SCI。除了 SCI 的发病延迟外,两组 SCI 的恢复过程相似。

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