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迁移至前房的地塞米松玻璃体内植入物(Ozurdex)的重新定位。

Repositioning of dexamethasone intravitreal implant (Ozurdex) migrated into the anterior chamber.

作者信息

Vela José I, Crespí Jaume, Andreu David

机构信息

Department of Ophthalmology, Institut Condal d'Oftalmologia, C/Aragó 469 4º 5º, 08013 Barcelona, Spain.

出版信息

Int Ophthalmol. 2012 Dec;32(6):583-4. doi: 10.1007/s10792-012-9604-7. Epub 2012 Jul 5.

DOI:10.1007/s10792-012-9604-7
PMID:22763812
Abstract

Ozurdex (Allergan Inc., Irvine, CA, USA) is a biodegradable implant of dexamethasone (0.7 mg) injected into the vitreous cavity to treat macular oedema. We report a case of migration of Ozurdex into the anterior chamber in a patient who had a previous iris-claw lens implantation. Surgical removal of the implant was avoided due to the absence of anterior complications and the loss of effectiveness of the drug delivery system. Repositioning of the implant to the posterior segment is described. This case illustrates the efficacy of this technique in cases of migration into the anterior chamber in eyes without corneal decompensation.

摘要

奥助得(美国加利福尼亚州尔湾市爱力根公司)是一种可生物降解的地塞米松植入物(0.7毫克),注入玻璃体腔用于治疗黄斑水肿。我们报告了一例曾植入虹膜爪状晶状体的患者,奥助得迁移至前房的病例。由于无前部并发症且药物递送系统失效,未进行植入物的手术取出。描述了将植入物重新定位至眼后段的方法。该病例说明了该技术在无角膜失代偿的眼中植入物迁移至前房的情况下的有效性。

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引用本文的文献

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Anterior migration of Ozurdex implant: a review on risk factors, complications, and management.Ozurdex植入物向前移位:关于危险因素、并发症及处理的综述
Int J Retina Vitreous. 2023 Nov 27;9(1):74. doi: 10.1186/s40942-023-00513-5.
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Active removal of anterior segment-migrated dexamethasone implant (Ozurdex).主动移除前段移位的地塞米松植入物(Ozurdex)。
GMS Ophthalmol Cases. 2022 Mar 22;12:Doc08. doi: 10.3205/oc000195. eCollection 2022.
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Hole-in-one: simple non-surgical technique for the management of anterior chamber migrated Ozurdex implant.

本文引用的文献

1
Wandering Ozurdex(®) implant.可植入式Ozurdex(®)缓释药物装置
J Ophthalmic Inflamm Infect. 2012 Mar;2(1):1-5. doi: 10.1007/s12348-011-0042-x. Epub 2011 Sep 30.
一杆进洞:用于处理前房内移位的Ozurdex植入物的简单非手术技术。
GMS Ophthalmol Cases. 2020 Feb 27;10:Doc05. doi: 10.3205/oc000132. eCollection 2020.
4
Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature.缓释地塞米松玻璃体内植入物的前房迁移:一例报告及文献综述
Oman J Ophthalmol. 2019 May-Aug;12(2):133-137. doi: 10.4103/ojo.OJO_5_2018.
5
Risk factors for and management of anterior chamber intravitreal dexamethasone implant migration.前房内玻璃体腔地塞米松植入物移位的危险因素及处理
BMC Ophthalmol. 2019 May 28;19(1):120. doi: 10.1186/s12886-019-1122-1.
6
Uneventful Anterior Migration of Intravitreal Ozurdex Implant in a Patient with Iris-Sutured Intraocular Lens and Descemet Stripping Automated Endothelial Keratoplasty.虹膜缝合人工晶状体及Descemet膜剥除自动内皮角膜移植术患者玻璃体内Ozurdex植入物的顺利前向移位
Case Rep Ophthalmol. 2018 Feb 14;9(1):143-148. doi: 10.1159/000486924. eCollection 2018 Jan-Apr.
7
Corneal graft failure due to migration of Ozurdex™ implant into the anterior chamber.由于Ozurdex™植入物迁移至前房导致的角膜移植失败。
Am J Ophthalmol Case Rep. 2017 Sep 1;8:25-27. doi: 10.1016/j.ajoc.2017.08.002. eCollection 2017 Dec.
8
New Drugs and New Posterior Delivery Methods in CME.继续医学教育中的新药与新型后路分娩方法
Curr Ophthalmol Rep. 2017 Jun;5(2):160-168. doi: 10.1007/s40135-017-0134-3. Epub 2017 Apr 7.
9
The nomadic Ozurdex: Anterior migration of the dexamethasone implant and back!游走的Ozurdex:地塞米松植入物的向前迁移及回归!
Oman J Ophthalmol. 2017 May-Aug;10(2):109-111. doi: 10.4103/0974-620X.209110.
10
The clinical outcomes of surgical management of anterior chamber migration of a dexamethasone implant (Ozurdex®).地塞米松植入物(Ozurdex®)前房移位的手术治疗临床结果
Graefes Arch Clin Exp Ophthalmol. 2017 Sep;255(9):1819-1825. doi: 10.1007/s00417-017-3705-y. Epub 2017 Jun 10.