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古菌中的防御和调控小 RNA

Small RNAs for defence and regulation in archaea.

机构信息

Biologie II, Ulm University, Albert-Einstein-Allee 11, 89069 Ulm, Germany.

出版信息

Extremophiles. 2012 Sep;16(5):685-96. doi: 10.1007/s00792-012-0469-5. Epub 2012 Jul 5.

Abstract

Non-coding RNAs are key players in many cellular processes within organisms from all three domains of life. The range and diversity of small RNA functions beyond their involvement in translation and RNA processing was first recognized for eukaryotes and bacteria. Since then, small RNAs were also found to be abundant in archaea. Their functions include the regulation of gene expression and the establishment of immunity against invading mobile genetic elements. This review summarizes our current knowledge about small RNAs used for regulation and defence in archaea.

摘要

非编码 RNA 是所有三个生命领域的生物体中许多细胞过程的关键参与者。小 RNA 的功能范围和多样性超出了它们在翻译和 RNA 处理中的参与,最初是在真核生物和细菌中被认识到的。从那时起,小 RNA 也在古菌中被发现大量存在。它们的功能包括调节基因表达和建立对抗入侵移动遗传元件的免疫。这篇综述总结了我们目前关于古菌中用于调节和防御的小 RNA 的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff6b/3432209/9280ea2cddb1/792_2012_469_Fig1_HTML.jpg

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