Monigel H, Stoll D, Aubry-Rozier B, Fetz G L, Theumann N, Lamy O
Centre de Maladie Osseuse, CHUV, Lausanne.
Praxis (Bern 1994). 2012 Jul 4;101(14):923-8. doi: 10.1024/1661-8157/a000990.
Pregnancy-associated osteoporosis usually appears during the first pregnancy and does not affect the followings. We report two cases where non-traumatic fractures have been diagnosed shortly after delivery of second pregnancies. Wide investigations could not find a cause of secondary osteoporosis. In the first case we came to the diagnosis of pregnancy-associated osteoporosis and an intravenous treatment of ibandronate has been prescribed. In the second case the bone mineral density (BMD) being almost normal and the localisation of the fracture being atypical, we concluded to a fracture of non-osteoporotic origin, probably due to mechanical stress during pregnancy. No therapy against osteoporosis has been prescribed.
妊娠相关性骨质疏松通常在首次妊娠期间出现,且不会影响后续情况。我们报告了两例在第二次妊娠分娩后不久被诊断为非创伤性骨折的病例。广泛检查未发现继发性骨质疏松的病因。第一例中,我们诊断为妊娠相关性骨质疏松,并开具了静脉注射伊班膦酸钠的治疗方案。第二例中,骨密度(BMD)几乎正常且骨折部位不典型,我们推断为非骨质疏松性骨折,可能是由于妊娠期间的机械应力所致。未开具抗骨质疏松治疗药物。