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骨质疏松性腰椎椎弓根螺钉翻修:椎体后凸成形术与经椎弓根聚甲基丙烯酸甲酯强化的生物力学比较

Revision of the failed pedicle screw in osteoporotic lumbar spine: biomechanical comparison of kyphoplasty versus transpedicular polymethylmethacrylate augmentation.

作者信息

Derinçek Alihan, Türker Mehmet, Cinar Murat, Cetik Ozgür, Kalaycioğlu Bariş

机构信息

Department of Orthopedics and Traumatology, Medical Faculty of Başkent University, Adana, Turkey.

出版信息

Eklem Hastalik Cerrahisi. 2012;23(2):106-10.

Abstract

OBJECTIVES

In this study, we aimed to compare of kyphoplasty versus transpedicular polymethylmethacrylate (PMMA) augmentation biomechanically in the revision of the failed pedicle screw in osteoporotic lumbar spine.

MATERIALS AND METHODS

Bone mineral density (BMD) of lumbar vertebrae collected from four bovines were measured. Each vertebra was decalcified with hydrochloric acid solution to obtain osteoporotic specimens. Primary polyaxial pedicle screws were inserted into the pedicles and pulled out until they failed. The pullout strength results of all specimens were recorded. Revision pedicle screws were randomly inserted into the same pedicles by either pedicle hole PMMA augmented (group 1) or kyphoplasty (Xvoid™) PMMA augmented pedicle screws (group 2). The pullout strength results of all specimens were re-recorded.

RESULTS

The mean BMD significantly decreased from 1.686 ± 227.9 g/cm(2) to 1.432 ± 157.1 g/cm(2) following decalcification (p<0.001). In group 1, the mean pullout strength of primary screws significantly decreased from 3443 ± 1086 N/m(2) to 2088 ± 924 N/m(2) following pedicle screw augmentation (p=0.006). In group 2, the mean pullout strength of primary screws decreased from 3702 ± 1063 N/m(2) to 3664 ± 1057 N/m(2) following kyphoplasty augmentation (p=0.934). Pedicle screw augmentation group achieved significantly lower pullout strength values than kyphoplasty pedicle hole augmentation group (p=0.002).

CONCLUSION

Although pedicle hole PMMA augmentation is the gold standard for the failed screws in an osteoporotic bone, kyphoplasty augmented pedicle screw seems to be more effective method increasing the pullout strength.

摘要

目的

在本研究中,我们旨在比较椎体后凸成形术与经椎弓根聚甲基丙烯酸甲酯(PMMA)强化在骨质疏松性腰椎椎弓根螺钉翻修中的生物力学差异。

材料与方法

测量从四头牛采集的腰椎骨密度(BMD)。用盐酸溶液对每个椎体进行脱钙以获得骨质疏松标本。将初次使用的多轴椎弓根螺钉插入椎弓根并拔出直至失效。记录所有标本的拔出强度结果。将翻修椎弓根螺钉通过椎弓根孔PMMA强化(第1组)或椎体后凸成形术(Xvoid™)PMMA强化椎弓根螺钉(第2组)随机插入相同的椎弓根。再次记录所有标本的拔出强度结果。

结果

脱钙后,平均骨密度从1.686±227.9 g/cm²显著降至至1.432±157.1 g/cm²(p<0.001)。在第1组中,椎弓根螺钉强化后,初次螺钉的平均拔出强度从3443±1086 N/m²显著降至2088±924 N/m²(p=0.006)。在第2组中,椎体后凸成形术强化后,初次螺钉的平均拔出强度从3702±1063 N/m²降至3664±1057 N/m²(p=0.934)。椎弓根螺钉强化组的拔出强度值显著低于椎体后凸成形术椎弓根孔强化组(p=0.002)。

结论

尽管椎弓根孔PMMA强化是骨质疏松性骨中失败螺钉的金标准,但椎体后凸成形术强化椎弓根螺钉似乎是提高拔出强度更有效的方法。

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