Bedossa P, Ngendayo L, Hervé P, Rain B, Poynard T, Simonneau G
Laboratoire d'Anatomie Pathologique, Hôpital Antoine-Béclère, Clamart.
Gastroenterol Clin Biol. 1990;14(11):881-4.
Two cases of nodular regenerative hyperplasia of the liver coexisting with pulmonary hypertension are described. Regarding its low frequency, nodular regenerative hyperplasia has been found more often than expected in our series of coexisting porto-pulmonary hypertension (2 out of 14 cases, 14 percent). In our 2 cases, pulmonary symptoms occurred before or simultaneously with hepatic symptoms. The high prevalence of this association and the unusual onset setting of symptoms suggest that this association is unfortuitous. A common pathogenesis for pulmonary and hepatic lesions is discussed.
本文描述了两例肝脏结节性再生性增生合并肺动脉高压的病例。鉴于其发病率较低，在我们一系列合并门脉性肺动脉高压的病例中，结节性再生性增生的发现频率高于预期（14例中有2例，占14%）。在我们的2例病例中，肺部症状先于或与肝脏症状同时出现。这种关联的高发生率以及症状出现的异常情况表明这种关联是偶然的。本文还讨论了肺部和肝脏病变的共同发病机制。
