Adis, Auckland, New Zealand.
Clin Drug Investig. 2012 Aug 1;32(8):555-60. doi: 10.1007/BF03261909.
Intravenous crotalidae polyvalent immune Fab (CroFab(®)) is effective in patients with minimal, moderate or severe crotaline envenomation, halting the progression of local venom effects and ameliorating haematological and other systemic abnormalities of envenomation. Despite treatment, patients may experience delayed-onset or recurrent venom effects (e.g. coagulopathy). Intravenous crotalidae polyvalent immune Fab is generally well tolerated, with acute hypersensitivity reactions being the most commonly occurring adverse event.
静脉用蝮蛇多价免疫 Fab 片段（CroFab(®)）对轻度、中度或重度蝮蛇咬伤患者有效，可阻止局部毒液作用的进展，并改善咬伤的血液学和其他全身异常。尽管进行了治疗，患者仍可能出现迟发性或复发性毒液作用（例如凝血功能障碍）。静脉用蝮蛇多价免疫 Fab 片段通常具有良好的耐受性，最常发生的不良反应是急性过敏反应。
