Division of Rheumatology, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clin Proc. 2012 Jul;87(7):659-73. doi: 10.1016/j.mayocp.2012.03.011.
The past decade has brought important advances in the understanding of rheumatoid arthritis and its management and treatment. New classification criteria for rheumatoid arthritis, better definitions of treatment outcome and remission, and the introduction of biologic response-modifying drugs designed to inhibit the inflammatory process have greatly altered the approach to managing this disease. More aggressive management of rheumatoid arthritis early after diagnosis and throughout the course of the disease has resulted in improvement in patient functioning and quality of life, reduction in comorbid conditions, and enhanced survival.
过去十年,人们对类风湿关节炎的认识及其治疗和管理取得了重要进展。新的类风湿关节炎分类标准、对治疗结果和缓解的更好定义,以及旨在抑制炎症过程的生物反应调节剂的引入,极大地改变了治疗这种疾病的方法。在诊断后和疾病过程中早期更积极地治疗类风湿关节炎,可改善患者的功能和生活质量,减少合并症,并提高生存率。