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脉搏血氧饱和度测定法在急性心力衰竭诊断中的应用

Pulse oximetry in the diagnosis of acute heart failure.

作者信息

Masip Josep, Gayà Maria, Páez Joaquim, Betbesé Antoni, Vecilla Francisco, Manresa Ruben, Ruíz Pilar

机构信息

Unidad de Cuidados Intensivos, Hospital Sant Joan Despí Moisès Broggi, Consorci Sanitari Integral, Universidad de Barcelona, Sant Joan Despí, Barcelona, España.

出版信息

Rev Esp Cardiol (Engl Ed). 2012 Oct;65(10):879-84. doi: 10.1016/j.recesp.2012.02.022. Epub 2012 Jul 4.

Abstract

INTRODUCTION AND OBJECTIVES

Oxygen saturation by pulse oximetry is commonly used for monitoring critical patients, but its utility as a diagnostic marker of acute heart failure has not been assessed. This study analyzed the diagnostic role of oxygen saturation by pulse oximetry in a series of patients with acute myocardial infarction.

METHODS

In a prospective observational cohort study of 220 consecutive patients with acute myocardial infarction, data collection included baseline oxygen saturation by pulse oximetry (without oxygen), physiologic measurements, Killip class and data from portable chest radiography, recorded at the same hour on each of the first three days after admission. Patients were followed up for one year.

RESULTS

There were 612 assessments. Baseline oxygen saturation by pulse oximetry decreased progressively in relation to the presence and the severity of acute heart failure assessed by Killip classes 1 to 3 (mean: 95, 92 and 85, respectively; P<.001) or by Radiology Score 0 to 4 (95, 94, 92, 89 and 83, respectively; P<.001), with a correlation coefficient of 0.66 and 0.63, respectively. Receiver operating characteristic curves disclosed the cut-off of oxygen saturation by pulse oximetry<93 to have the greatest area, with a sensitivity of 65%, specificity 90%, and overall test accuracy 83%. Patients grouped according to lowest oxygen saturation by pulse oximetry showed significantly different rates of one-year mortality or rehospitalization for heart failure.

CONCLUSIONS

Baseline oxygen saturation by pulse oximetry is useful in establishing the diagnosis and severity of heart failure in acute settings such as myocardial infarction and may have prognostic implications.The diagnosis may be suspected when baseline oxygen saturation by pulse oximetry is <93. Full English text available from:www.revespcardiol.org.

摘要

引言与目的

通过脉搏血氧饱和度测定法测量的血氧饱和度常用于监测重症患者,但其作为急性心力衰竭诊断标志物的效用尚未得到评估。本研究分析了脉搏血氧饱和度测定法在一系列急性心肌梗死患者中的诊断作用。

方法

在一项对220例连续急性心肌梗死患者的前瞻性观察队列研究中,数据收集包括入院后前三天每天同一时间通过脉搏血氧饱和度测定法测量的基线血氧饱和度(未吸氧时)、生理测量值、Killip分级以及便携式胸部X光片数据。对患者进行了为期一年的随访。

结果

共进行了612次评估。通过脉搏血氧饱和度测定法测量的基线血氧饱和度随着Killip分级1至3级(分别为95、92和85;P<0.001)或放射学评分0至4级(分别为95、94、92、89和83;P<0.001)评估的急性心力衰竭的存在和严重程度而逐渐降低,相关系数分别为0.66和0.63。受试者工作特征曲线显示,脉搏血氧饱和度测定法的血氧饱和度临界值<93时曲线下面积最大,灵敏度为65%,特异性为90%,总体检测准确性为83%。根据脉搏血氧饱和度测定法测得的最低血氧饱和度分组的患者,其一年死亡率或因心力衰竭再次住院的发生率有显著差异。

结论

在心肌梗死等急性情况下,通过脉搏血氧饱和度测定法测量的基线血氧饱和度有助于诊断心力衰竭及其严重程度,可能具有预后意义。当通过脉搏血氧饱和度测定法测量的基线血氧饱和度<93时,可能提示心力衰竭。完整英文文本可从:www.revespcardiol.org获取。

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