Department of Cardiology, School of Medicine, Marmara University, Kadikoy, Istanbul, Turkey.
Europace. 2013 Apr;15(4):590-4. doi: 10.1093/europace/eus211. Epub 2012 Jul 5.
Recording electrocardiograms (ECGs) by placing the right precordial leads at higher intercostal spaces (ICSs) increases the sensitivity for detecting Brugada-type ECG pattern (BTEP). Published studies unfortunately used standard lead positions for recording ECGs and underestimated the true prevalence of BTEP. Therefore, by placing right precordial leads at higher ICS, we aimed to find out the true prevalence of BTEP in our population.
Healthy male volunteers (n= 504) between 18 and 55 years of age (37.3 ± 10.7 years) without known cardiac or metabolic disorders were enrolled into the study. After the standard ECG recording, two other recordings were obtained by placing the right precordial leads to the third and second ICS. Electrocardiograms were stratified by two independent reviewers for the presence of BTEP. There were 15 subjects (3%) who displayed BTEP on their standard ECG recordings. Number of cases displaying BTEP increased to 25 (5%) and 38 (7.5%) when the right precordial leads were moved to third and second ICS, respectively. Although none of the subjects displayed type 1 BTEP on their standard ECGs, three subjects displayed type 1 BTEP on the third and four subjects displayed type 1 BTEP on the second ICS.
Our study revealed that the prevalence of BTEP in healthy male subjects was 7.5% by placing the right precordial leads to higher ICS. Instead of standard lead locations that are not sensitive enough for detection of BTEP we recommend high right ICS recording in further prevalence studies.
通过将右侧胸前导联放置在较高的肋间间隙（ICS）记录心电图（ECG）可以提高检测 Brugada 型心电图模式（BTEP）的敏感性。然而，已发表的研究不幸地使用了标准导联位置记录 ECG，并低估了 BTEP 的真实患病率。因此，通过将右侧胸前导联放置在较高的 ICS，我们旨在确定我们人群中 BTEP 的真实患病率。
本研究纳入了 504 名年龄在 18 至 55 岁之间（37.3 ± 10.7 岁）的健康男性志愿者，他们没有已知的心脏或代谢疾病。在进行标准 ECG 记录后，通过将右侧胸前导联放置在第三和第二 ICS 获得另外两个记录。心电图由两名独立的评审员进行分层，以评估是否存在 BTEP。在标准 ECG 记录中，有 15 名受试者（3%）显示出 BTEP。当右侧胸前导联移至第三和第二 ICS 时，显示 BTEP 的病例数分别增加至 25（5%）和 38（7.5%）。尽管在标准 ECG 上没有受试者显示 1 型 BTEP，但有 3 名受试者在第三 ICS 上显示 1 型 BTEP，有 4 名受试者在第二 ICS 上显示 1 型 BTEP。
通过将右侧胸前导联放置在较高的 ICS，我们发现健康男性受试者中 BTEP 的患病率为 7.5%。我们建议在进一步的患病率研究中使用对 BTEP 检测不够敏感的标准导联位置，而采用较高的右侧 ICS 记录。
