A piezogenic papule with histopathologic features simulating angiomyxolipoma.

Piezogenic papules are lesions that occur on the feet and wrists because of the herniation of fat through the dermis. These papules can be painful or completely asymptomatic. Poor compartmentalization of fat occurs because of thinner than normal fibrous trabeculae and contributes to the formation of piezogenic papules. On histological examination, fat is evident extending through the dermis. We report a case of a piezogenic papule simulating angiomyxolipoma on histological examination. The presented case suggests the possibility of an association between herniated fat tissue and mucin deposition with vascular proliferation.