Song Wei, Yang Jinrui, Huang Li
Department of Urology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Jun;37(6):633-6. doi: 10.3969/j.issn.1672-7347.2012.06.016.
To investigate the diagnosis and surgical treatment of adrenocortical oncocytoma. The clinical data from three cases of adrenocortical oncocytomas (ACOs) were retrospectively analyzed and discussed in light of the relevant literature. In these three cases, one presented with virilization, while the other two cases had no typical clinical features. The tumor was completely encapsulated and was non-invasive. Microscopically, the tumor cells showed neither mitosis nor necrosis, with abundant eosinophilic cytoplasm. No recurrence or metastasis was discovered after close follow-up observation for 12-24 months. Adrenocortical ACOs are rather rare, and most of them are benign. It was hard to make a confirmed diagnosis of ACOs before surgery. Resection of tumor is the best choice, and close follow-up observation is essential.
探讨肾上腺皮质嗜酸细胞瘤的诊断及手术治疗方法。回顾性分析3例肾上腺皮质嗜酸细胞瘤（ACO）的临床资料，并结合相关文献进行讨论。这3例患者中，1例表现为男性化，另外2例无典型临床特征。肿瘤完全被包膜包裹，无浸润性。镜下，肿瘤细胞未见有丝分裂及坏死，胞质丰富、嗜酸性。经12 - 24个月的密切随访观察，未发现复发或转移。肾上腺皮质ACO较为罕见，多数为良性。术前很难确诊ACO。肿瘤切除是最佳选择，密切随访观察至关重要。
