DiCaprio R A
Department of Zoological and Biomedical Sciences, Ohio University, Athens 45701.
J Exp Biol. 1990 Nov;154:517-35. doi: 10.1242/jeb.154.1.517.
The central pattern generator controlling ventilation in the crab can generate two distinct motor programmes, which determine the direction of water flow during irrigation of the gills. An interneurone has been identified that depolarizes when the ventilatory motor output switches from forward to reverse ventilation and remains depolarized for the duration of the reverse motor programme. Depolarization of this neurone by intracellular current injection causes a switch in the motor programme from forward to reverse ventilation, which persists for the duration of the current step. Hyperpolarization of this cell during reverse ventilation terminates the reverse motor programme. The possible role of this reversal switch interneurone is considered in the context of the observed changes in the activity of other ventilatory interneurones and motor neurones during reverse ventilation.
控制螃蟹呼吸的中枢模式发生器能够产生两种不同的运动程序，这两种程序决定了鳃部冲水时水流的方向。已识别出一种中间神经元，当通气运动输出从正向通气切换为反向通气时，该神经元会发生去极化，并在反向运动程序持续期间保持去极化状态。通过细胞内电流注入使该神经元去极化会导致运动程序从正向通气切换为反向通气，并在电流注入步骤持续期间一直保持这种状态。在反向通气期间对该细胞进行超极化会终止反向运动程序。结合在反向通气期间观察到的其他通气中间神经元和运动神经元活动的变化，对这种反向切换中间神经元的可能作用进行了探讨。
