Senanayake N
Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.
J Neurol. 1990 Oct;237(6):388-91. doi: 10.1007/BF00315667.
Eating-related seizures affecting 20 individuals among 59 siblings belonging to nine families are presented. The type of epilepsy was partial in all the affected individuals, and the seizures complex in 15 and simple in 5, secondarily generalized in the majority. The onset of epilepsy, in most cases, was in the second decade of life. A remarkable degree of intra-family consistency was observed with regard to age at onset, symptomatology of seizures and timing of eating seizures. The study demonstrates sibling clustering in a partial epilepsy, implicating for the first time genetic susceptibility in the aetiology of eating epilepsy.
本文报告了来自9个家庭的59名兄弟姐妹中有20人出现与进食相关的癫痫发作。所有受影响个体的癫痫类型均为部分性发作，其中15人为复杂部分性发作，5人为简单部分性发作，大多数继发全面性发作。癫痫发作大多始于生命的第二个十年。在发病年龄、癫痫发作症状学和进食性癫痫发作时间方面，观察到显著的家族内一致性。该研究表明部分性癫痫存在同胞聚集现象，首次提示遗传易感性在进食性癫痫病因学中的作用。
