Naproxen parenteral formulation studies.

Naproxen sodium has been formulated in a parenteral dosage form. After a series of experiments involving solubility, pH, and excipient compatibility using Placket Burman experimental design, the formulation has been finalized. The accelerated stability studies on samples stored at high temperatures projected the shelf life to be 4.2 years. Toxicological, therapeutic efficacy, and other aspects of this formulation are being reported separately.