Kliniczny Oddział Neurologii z Pododdziałem Chorób Układu Pozapiramidowego, III Szpital Miejski im. dr. Karola Jonschera w Lodzi.
Neurol Neurochir Pol. 2012 May-Jun;46(3):284-7. doi: 10.5114/ninp.2012.29136.
POEMS syndrome is a rare multisystem disorder, characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. The variety of clinical pictures and asynchronous manifestation of dominant features make diagnosis difficult. We report a case of a 42-year-old man with polyneuropathy who was initially negative for monoclonal protein and so Guillain-Barré syndrome was diagnosed. Other signs and symptoms, including monoclonal gammopathy, developed later in the course of the disease and finally POEMS syndrome was diagnosed.
POEMS 综合征是一种罕见的多系统疾病，其特征为多发性神经病、器官肿大、内分泌病、单克隆丙种球蛋白病和皮肤改变。各种临床表现和主要特征的不同时出现使得诊断变得困难。我们报告了一例 42 岁男性，其首发症状为多发性神经病，初始时无单克隆蛋白，因此被诊断为吉兰-巴雷综合征。其他征象和症状，包括单克隆丙种球蛋白病，在疾病过程中后来才出现，最终被诊断为 POEMS 综合征。
