PhotoGreen Lab, Department of Chemistry, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.
J Org Chem. 2012 Aug 3;77(15):6473-9. doi: 10.1021/jo3010183. Epub 2012 Jul 17.
2-Substituted benzo[b]furans were synthesized by a one-step metal-free photochemical reaction between 2-chlorophenol derivatives and terminal alkynes by tandem formation of an aryl-C and a C-O bond via an aryl cation intermediate. The mild conditions and the application to chlorophenols rather of the more expensive bromo or iodo analogues makes this procedure environmentally convenient.
2-取代苯并[b]呋喃通过 2-氯苯酚衍生物和末端炔烃之间的一步无金属光化学反应，通过芳基阳离子中间体串联形成芳基-C 和 C-O 键来合成。温和的条件以及对氯苯酚的应用而不是更昂贵的溴或碘类似物，使该方法具有环境友好性。
