Private practice, Maringá, PR, Brazil Department of Dentistry, State University of Maringá, Maringá, PR, Brazil.
J Periodontal Res. 2012 Dec;47(6):758-65. doi: 10.1111/j.1600-0765.2012.01491.x. Epub 2012 Jul 8.
Successful root-coverage treatment depends on the thickness of the donor tissue. This study aimed to evaluate the thickness of donor tissue after augmentation of the connective tissue in the palatal area by implantation of lyophilized collagen sponge (Hemospon(®) ).
Ten patients with an indication for root coverage, whose palate was deficient in adequate connective tissue, were recruited. The procedure was carried out in two stages. In the first stage, the palatal thickness in the donor site was measured at three standardized points (points 1, 2 and 3), from the distal of the canine to the distal of the first molar, and the lyophilized collagen sponge was inserted. In the second stage, the palatal thickness over the implant was measured (at points 1, 2 and 3), two biopsies of the palatal mucosa were collected - one over the implant (experimental sample) and the other on the contralateral side (control sample) - and then root-coverage treatment was performed. Analyses consisted of clinical assessment of the palatal measurements before and after sponge implantation, and histological assessment of the experimental and control biopsy samples. Data were analyzed using the Wilcoxon test.
Both analyses showed a significant increase in mean thickness, of 1.08 mm of neoformed tissue in the clinical analysis (the tissue at point 2 was the thickest of the three points) and of 0.53 mm in the histological analysis.
The insertion of lyophilized collagen sponge induced a significant increase in the thickness of palatal connective tissue.
成功的根覆盖治疗取决于供体组织的厚度。本研究旨在评估通过在腭部植入冻干胶原海绵（Hemospon®）来增加结缔组织后供体组织的厚度。
10 名有根覆盖适应证且腭部缺乏足够结缔组织的患者被纳入研究。该程序分两阶段进行。在第一阶段，在三个标准化点（犬齿远中至第一磨牙远中处的点 1、2 和 3）测量供体部位的腭部厚度，并插入冻干胶原海绵。在第二阶段，测量植入物上方的腭部厚度（在点 1、2 和 3），采集腭黏膜的两个活检样本-一个在植入物上方（实验样本），另一个在对侧（对照样本）-然后进行根覆盖治疗。分析包括植入海绵前后腭部测量的临床评估，以及实验和对照活检样本的组织学评估。使用 Wilcoxon 检验进行数据分析。
两种分析均显示出平均厚度的显著增加，临床分析中为 1.08 毫米的新形成组织（三个点中以点 2 最厚），组织学分析中为 0.53 毫米。
冻干胶原海绵的插入导致腭部结缔组织厚度显著增加。
