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加泰罗尼亚成人重症监护病房器械相关感染率:VINCat 项目研究结果。

Device-associated infection rates in Adult Intensive Care Units in Catalonia: VINCat Program findings.

机构信息

Critical Care Unit, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Sabadell, Barcelona, Spain. CIBER Enfermedades Respiratorias.

出版信息

Enferm Infecc Microbiol Clin. 2012 Jun;30 Suppl 3:33-8. doi: 10.1016/S0213-005X(12)70094-0.

DOI:10.1016/S0213-005X(12)70094-0
PMID:22776152
Abstract

Hospital-acquired infections are a leading cause of morbidity and mortality, especially in the intensive care unit (ICU). Surveillance of device-associated infections plays a major role in infection control programs. In 2006, the Surveillance Program of Nosocomial Infections in Catalonia (VINCat Program) was started, with the major aim of reducing infection rates through a process of active monitoring. The study period comprised calendar years 2008 (with 21 ICUs participating), 2009 (with 21 ICUs participating), and 2010 (with 28 ICUs participating). Each participating hospital was required to have an infection control team made up of at least one physician, an infection surveillance nurse, and a microbiology laboratory. Hospitals were classified into three groups according to their size. Central venous catheter-associated bloodstream infection (CVC-BSI) and ventilator-associated pneumonia (VAP) were chosen as the device-associated infections to analyze. Incidence rates of device-associated infections were calculated by dividing the total number of device-associated infection (VAP or CVC-BSI) days by the total number of days use for the relevant device. Mechanical ventilation use ranged from 0.10 to 0.85 days (overall, 0.35), and central venous catheter use ranged from 0.18 to 0.98 days (overall, 0.65). Incidence rates of VAP ranged from 7.2 ± 3.7 to 10.7 ± 9.6 episodes of VAP/1000 ventilator days. Incidence rates of CVC-BSl ranged from 1.9 ± 1.6 to 2.7 ± 2.0 episodes of CVC-associated bloodstream infection/1000 central venous catheter days. The implementation of the VINCat Program allowed monitoring of nosocomial device-associated infections in ICUs in Catalonia and enabled corrective measures in ICUs with increased incidences of device-associated infections.

摘要

医院获得性感染是发病率和死亡率的主要原因,尤其是在重症监护病房(ICU)。器械相关感染的监测在感染控制计划中起着重要作用。2006 年,启动了加泰罗尼亚医院感染监测计划(VINCat 计划),其主要目的是通过主动监测来降低感染率。研究期间包括 2008 年(21 个 ICU 参与)、2009 年(21 个 ICU 参与)和 2010 年(28 个 ICU 参与)的历年。每个参与医院都必须有一个感染控制小组,由至少一名医生、一名感染监测护士和一个微生物实验室组成。医院根据规模分为三组。选择中心静脉导管相关血流感染(CVC-BSI)和呼吸机相关肺炎(VAP)作为分析的器械相关感染。器械相关感染的发病率是通过将器械相关感染(VAP 或 CVC-BSI)天数除以相关器械使用总天数来计算的。机械通气使用时间从 0.10 到 0.85 天(总平均为 0.35),中心静脉导管使用时间从 0.18 到 0.98 天(总平均为 0.65)。VAP 的发病率从 7.2 ± 3.7 到 10.7 ± 9.6 例 VAP/1000 机械通气日不等。CVC-BSl 的发病率从 1.9 ± 1.6 到 2.7 ± 2.0 例 CVC 相关血流感染/1000 中心静脉导管日不等。VINCat 计划的实施允许监测加泰罗尼亚 ICU 中的医院获得性器械相关感染,并能够对器械相关感染发生率较高的 ICU 采取纠正措施。

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