Molecular biology and clinical features of hereditary non-polyposis colorectal cancer.
作者信息
Guan Sha-sha, Dai Guang-hai
机构信息
Department of Multimodality Therapy Oncology, Chinese PLA Hospital, Beijing 100853, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Jun;34(3):293-7. doi: 10.3881/j.issn.1000-503X.2012.03.021.
Abstract
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.
摘要
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