Laumonier H, Leblanc F, Balabaud C, Bioulac-Sage P
Department of Radiology, Hôpital St André CHU Bordeaux, Bordeaux, France.
BMJ Case Rep. 2010 Sep 29;2010:bcr0220102704. doi: 10.1136/bcr.02.2010.2704.
Focal nodular hyperplasia (FNH) is a benign tumour of the liver, occurring in 0.6-3% of the general population. Most lesions are diagnosed incidentally. With the increasing use and improvement of diagnostic imaging, FNH is being observed more often. It has been shown, using radiological approaches, that most FNH remain stable, or even regress, over a long follow-up period. In addition, it is extremely rare that FNH were discovered in elderly. However, to our knowledge, there is no pathological report illustrating the regression of FNH. We report here a case showing the pathological changes occurring during the regression phase of FNH, with dense fibrous tissue mixed with arteries replacing hepatocytes nodules.
局灶性结节性增生(FNH)是一种肝脏良性肿瘤,在普通人群中的发生率为0.6%-3%。大多数病变是偶然发现的。随着诊断性影像学的应用增加和技术改进,FNH的发现越来越频繁。放射学研究表明,大多数FNH在长期随访中保持稳定,甚至缩小。此外,FNH在老年人中极为罕见。然而,据我们所知,尚无关于FNH消退的病理学报告。我们在此报告一例显示FNH消退期病理变化的病例,其中致密纤维组织与动脉混合取代了肝细胞结节。