Acharya Vikas, Williams Adam, Adams William, Hilton David, Whitfield Peter C
Department of General Medicine, Luton and Dunstable Hospital NHS Trust, Luton, UK.
BMJ Case Rep. 2012 Jul 9;2012:bcr1220115356. doi: 10.1136/bcr.12.2011.5356.
The authors present the unusual case of a 37-year-old man, with a history of hepatitis C, presenting with a 3 year history of progressive trigeminal, facial and vestibular nerve defects. Intracranial imaging demonstrated a cystic middle and posterior fossa lesion, that was ultimately diagnosed as a cystic trigeminal schwannoma. Due to the uncertainties of diagnosis he was managed in two stages with an open biopsy and then a subsequent partial resection. Surveillance of the tumour remnant is planned. The rare nature of this diagnosis is discussed, along with the more common findings in intracranial schwannoma, and the wide differential to be considered. Briefly, the authors describe the surgical option for a complex multi-fossa schwannoma and the importance of the multi-disciplinary team in the diagnosis and management of such patients.
作者报告了一例37岁男性的罕见病例,该患者有丙型肝炎病史,出现进行性三叉神经、面神经和前庭神经缺损3年。颅内影像学检查显示中颅窝和后颅窝有一个囊性病变,最终诊断为囊性三叉神经鞘瘤。由于诊断存在不确定性,患者分两个阶段进行治疗,先进行开放性活检,随后进行部分切除。计划对肿瘤残余进行监测。文中讨论了该诊断的罕见性、颅内神经鞘瘤更常见的表现以及需要考虑的广泛鉴别诊断。简而言之,作者描述了复杂多颅窝神经鞘瘤的手术选择以及多学科团队在这类患者诊断和管理中的重要性。