Suppr超能文献

对牙科汞合金毒性的恐惧:是谣言还是事实。

The dental amalgam toxicity fear: a myth or actuality.

作者信息

Rathore Monika, Singh Archana, Pant Vandana A

机构信息

Department of Pedodontics, BBD College of Dental Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Toxicol Int. 2012 May;19(2):81-8. doi: 10.4103/0971-6580.97191.

Abstract

Amalgam has been used in dentistry since about 150 years and is still being used due to its low cost, ease of application, strength, durability, and bacteriostatic effect. When aesthetics is not a concern it can be used in individuals of all ages, in stress bearing areas, foundation for cast-metal and ceramic restorations and poor oral hygiene conditions. Besides all, it has other advantages like if placed under ideal conditions, it is more durable and long lasting and least technique sensitive of all restorative materials, but, concern has been raised that amalgam causes mercury toxicity. Mercury is found in the earth's crust and is ubiquitous in the environment, so even without amalgam restorations everyone is exposed to small but measurable amount of mercury in blood and urine. Dental amalgam restorations may raise these levels slightly, but this has no practical or clinical significance. The main exposure to mercury from dental amalgam occurs during placement or removal of restoration in the tooth. Once the reaction is complete less amount of mercury is released, and that is far below the current health standard. Though amalgam is capable of producing delayed hypersensitivity reactions in some individuals, if the recommended mercury hygiene procedures are followed the risks of adverse health effects could be minimized. For this review the electronic databases and PubMed were used as data sources and have been evaluated to produce the facts regarding amalgam's safety and toxicity.

摘要

银汞合金在牙科领域已使用了约150年,由于其成本低、易于应用、强度高、耐久性好以及具有抑菌作用,至今仍在使用。当美观不是主要考虑因素时,它可用于所有年龄段的人群,用于承受压力的区域、铸造金属和陶瓷修复体的基底以及口腔卫生状况较差的情况。除此之外,它还有其他优点,比如在理想条件下放置时,它比所有修复材料更耐用、持久,且对技术的敏感性最低。但是,有人担心银汞合金会导致汞中毒。汞存在于地壳中,在环境中无处不在,所以即使没有银汞合金修复体,每个人血液和尿液中都会接触到少量但可测量的汞。牙科银汞合金修复体可能会使这些汞含量略有升高,但这并无实际或临床意义。牙科银汞合金导致汞暴露的主要途径是在牙齿中放置或去除修复体的过程。一旦反应完成,释放的汞量会减少,且远低于当前的健康标准。虽然银汞合金在某些个体中可能会引发迟发型超敏反应,但如果遵循推荐的汞卫生程序,健康受到不良影响的风险可以降至最低。在本次综述中,电子数据库和PubMed被用作数据源,并经过评估以得出有关银汞合金安全性和毒性的事实。

相似文献

1
The dental amalgam toxicity fear: a myth or actuality.
Toxicol Int. 2012 May;19(2):81-8. doi: 10.4103/0971-6580.97191.
2
Direct composite resin fillings versus amalgam fillings for permanent posterior teeth.
Cochrane Database Syst Rev. 2021 Aug 13;8(8):CD005620. doi: 10.1002/14651858.CD005620.pub3.
3
The potential adverse health effects of dental amalgam.
Toxicol Rev. 2005;24(1):1-10. doi: 10.2165/00139709-200524010-00001.
5
The release of mercury from amalgam restorations and its health effects: a review.
Oper Dent. 2009 Sep-Oct;34(5):605-14. doi: 10.2341/08-072-LIT.
6
Release of mercury vapor from dental amalgam.
Swed Dent J Suppl. 1992;85:1-52.
7
Pathway to mercury-free dentistry: an insight into past, present, and future.
Eur Oral Res. 2023 May 4;57(2):60-67. doi: 10.26650/eor.20231050091.
8
The safe and effective use of dental amalgam.
Int Dent J. 1987 Sep;37(3):147-51.
9
Neurobehavioral effects of dental amalgam in children: a randomized clinical trial.
JAMA. 2006 Apr 19;295(15):1784-92. doi: 10.1001/jama.295.15.1784.
10
Direct composite resin fillings versus amalgam fillings for permanent or adult posterior teeth.
Cochrane Database Syst Rev. 2014 Mar 31(3):CD005620. doi: 10.1002/14651858.CD005620.pub2.

引用本文的文献

4
Association between DMFT and primary headaches: a study based on the Rafsanjan cohort study.
BMC Oral Health. 2024 Jan 4;24(1):21. doi: 10.1186/s12903-023-03815-0.
5
Biocompatibility Testing for Implants: A Novel Tool for Selection and Characterization.
Materials (Basel). 2023 Oct 26;16(21):6881. doi: 10.3390/ma16216881.
6
Assessment of Cytotoxic and Genotoxic Effect of Modern Dental Materials .
Acta Stomatol Croat. 2023 Sep;57(3):216-228. doi: 10.15644/asc57/3/2.
8
Association between caregiver opposition to topical fluoride and COVID-19 vaccines.
Vaccine. 2023 Jan 27;41(5):1035-1041. doi: 10.1016/j.vaccine.2022.12.018. Epub 2022 Dec 14.
9
Bioactive Materials for Next-Generation Dentistry.
Bioengineering (Basel). 2022 Dec 8;9(12):782. doi: 10.3390/bioengineering9120782.
10
Urothelial Bladder Carcinoma in Students at a Dental Technical College: A Report of 3 Cases.
Case Rep Oncol. 2022 May 23;15(2):553-559. doi: 10.1159/000524826. eCollection 2022 May-Aug.

本文引用的文献

1
Mercury sensitisation: review, relevance and a clinical report.
Br Dent J. 2008 Oct 11;205(7):373-8. doi: 10.1038/sj.bdj.2008.843.
2
Metal allergens of growing significance: epidemiology, immunotoxicology, strategies for testing and prevention.
Inflamm Allergy Drug Targets. 2008 Sep;7(3):145-62. doi: 10.2174/187152808785748146.
3
Dental amalgam and psychosocial status: the New England Children's Amalgam Trial.
J Dent Res. 2008 May;87(5):470-4. doi: 10.1177/154405910808700504.
4
Local adverse effects of amalgam restorations.
Int Dent J. 2008 Feb;58(1):3-9. doi: 10.1111/j.1875-595x.2008.tb00170.x.
5
Renal effects of dental amalgam in children: the New England children's amalgam trial.
Environ Health Perspect. 2008 Mar;116(3):394-9. doi: 10.1289/ehp.10504.
7
Scalp hair and urine mercury content of children in the Northeast United States: the New England Children's Amalgam Trial.
Environ Res. 2008 May;107(1):79-88. doi: 10.1016/j.envres.2007.08.015. Epub 2007 Oct 24.
8
The contribution of dental amalgam to urinary mercury excretion in children.
Environ Health Perspect. 2007 Oct;115(10):1527-31. doi: 10.1289/ehp.10249.
9
Maternal amalgam dental fillings as the source of mercury exposure in developing fetus and newborn.
J Expo Sci Environ Epidemiol. 2008 May;18(3):326-31. doi: 10.1038/sj.jes.7500606. Epub 2007 Sep 12.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验