Laboratory of Molecular Imaging and Radiochemistry, Nuclear Medicine Clinic, Friedrich-Alexander University, Schwabachanlage 6, D-91054 Erlangen, Germany.
Curr Med Chem. 2012;19(23):3957-66. doi: 10.2174/092986712802002518.
This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the (11)C- and (18)F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.
这篇综述概述了用于通过正电子发射断层扫描（PET）对多巴胺受体表达进行体内成像的亚型选择性多巴胺受体放射性配体。除了已经临床应用的（11）C-和（18）F 标记放射性配体外，还提供了已在体外和体内研究过的亚型选择性放射性配体的总结，这为放射性药物研究领域的现状和最新进展提供了线索。
