Liudinovskova R A, Gromova G V, Tsygankova S T, Tarichko Iu V, Ivanov V A, Buniatian K A, Akimova N I, Tokareva L V
Vestn Akad Med Nauk SSSR. 1990(10):26-8.
The immune status, i.e. T and B lymphocytes and their populations, was assessed after heart valve replacement or reconstruction in 70 patients with acquired heart defects. In 30%, the immune status was found to be normal which corresponded to inactive rheumatic process in these patients; 40% showed activated immunity manifested by increased T-active, T-total, T-helper, and T-suppressor numbers compared to the first group, which corresponded to activation of a rheumatic process in these patients. The rest 30% patients showed suppressed immunity, i.e. diminished subpopulations of T lymphocytes and B lymphocytes. These changes were detected in patients with circulatory insufficiency and progressive septic endocarditis. This allows for a conclusion that determination of the status of immunity and its correction are essential for cardiac surgery patients.
对70例后天性心脏缺陷患者进行心脏瓣膜置换或重建术后，评估其免疫状态，即T淋巴细胞和B淋巴细胞及其亚群。结果发现，30%的患者免疫状态正常，这与这些患者风湿过程不活跃相对应；40%的患者表现为免疫激活，与第一组相比，其T活性、T总数、T辅助细胞和T抑制细胞数量增加，这与这些患者风湿过程的激活相对应。其余30%的患者表现为免疫抑制，即T淋巴细胞和B淋巴细胞亚群减少。这些变化在循环功能不全和进行性感染性心内膜炎患者中被检测到。由此可以得出结论，确定免疫状态并进行纠正对心脏手术患者至关重要。
