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Paediatric rheumatic disease: lessons from SLE: children are not little adults.

作者信息

Ardoin Stacy P, Schanberg Laura E

出版信息

Nat Rev Rheumatol. 2012 Aug;8(8):444-5. doi: 10.1038/nrrheum.2012.109. Epub 2012 Jul 10.

DOI:10.1038/nrrheum.2012.109
PMID:22782004
Abstract
摘要

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Paediatric rheumatic disease: lessons from SLE: children are not little adults.儿科风湿性疾病：系统性红斑狼疮的教训：儿童不是小大人。
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2
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3
[Diffuse alveolar hemorrhage in systemic lupus erythematosus].[系统性红斑狼疮中的弥漫性肺泡出血]
Zhonghua Yi Xue Za Zhi. 2009 Jan 20;89(3):201-3.
4
What's new in paediatric SLE?儿科红斑狼疮有哪些新进展？
Best Pract Res Clin Rheumatol. 2009 Oct;23(5):699-708. doi: 10.1016/j.berh.2009.07.008.
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Late-onset systemic lupus erythematosus: Is it "mild lupus"?迟发性系统性红斑狼疮：它是“轻度狼疮”吗？
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Lupus. 2016 Jan;25(1):75-80. doi: 10.1177/0961203315605365. Epub 2015 Sep 18.
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Differences in Clinical Features and Mortality between Childhood-onset and Adult-onset Systemic Lupus Erythematosus: A Prospective Single-center Study.儿童期起病与成人期起病的系统性红斑狼疮临床特征及死亡率的差异：一项前瞻性单中心研究
J Rheumatol. 2016 Aug;43(8):1490-7. doi: 10.3899/jrheum.151129. Epub 2016 Jun 1.
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Next generation sequencing analysis reveals complex genetic architecture of childhood-onset systemic lupus erythematosus.下一代测序分析揭示了儿童期系统性红斑狼疮的复杂遗传结构。
Lupus Sci Med. 2025 Jun 10;12(1):e001475. doi: 10.1136/lupus-2024-001475.
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Childhood-Onset Systemic Lupus Erythematosus (cSLE): An International Perspective.儿童发病系统性红斑狼疮(cSLE)：国际视角。
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本文引用的文献

1
Alveolar hemorrhage: distinct features of juvenile and adult onset systemic lupus erythematosus.肺泡出血：青少年和成人发病系统性红斑狼疮的特征性表现。
Lupus. 2012 Jul;21(8):872-7. doi: 10.1177/0961203312441047. Epub 2012 Mar 16.
2
Childhood-onset disease carries a higher risk of low bone mineral density in an adult population of systemic lupus erythematosus.幼年起病的系统性红斑狼疮患者成年后患低骨密度的风险更高。
Rheumatology (Oxford). 2012 Mar;51(3):468-75. doi: 10.1093/rheumatology/ker306. Epub 2011 Nov 16.
3
Use of atorvastatin in systemic lupus erythematosus in children and adolescents.
全球儿科风湿病学中医疗保健的不平等现象。
Best Pract Res Clin Rheumatol. 2024 Sep;38(3):101983. doi: 10.1016/j.berh.2024.101983. Epub 2024 Jul 26.
4
Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus.全基因组数据在儿童发病系统性红斑狼疮中的传递不平衡分析。
Genes Immun. 2023 Aug;24(4):200-206. doi: 10.1038/s41435-023-00214-x. Epub 2023 Jul 24.
5
"There's so much to be done": a qualitative study to elucidate research priorities in childhood-onset systemic lupus erythematosus.“有太多的事情要做”：一项阐明儿童发病系统性红斑狼疮研究重点的定性研究。
Lupus Sci Med. 2022 Mar;9(1). doi: 10.1136/lupus-2022-000659.
6
Kidney Function, Age, and Education as Contributors to Depression and Anxiety in Juvenile Systemic Lupus Erythematosus.肾功能、年龄和教育程度对青少年系统性红斑狼疮患者抑郁和焦虑的影响
Eur J Investig Health Psychol Educ. 2021 Nov 25;11(4):1503-1515. doi: 10.3390/ejihpe11040107.
7
Th cytokine profile in childhood-onset systemic lupus erythematosus.儿童发病系统性红斑狼疮的细胞因子谱。
BMC Pediatr. 2021 Apr 21;21(1):187. doi: 10.1186/s12887-021-02659-3.
8
Ethical Drug Development for Rare Childhood Diseases: When There Are Limited But Promising Data in Adults, How to Choose Between Safety or Efficacy Studies?罕见儿童疾病的伦理药物研发：当成人数据有限但前景乐观时，如何在安全性研究和有效性研究之间做出选择？
Am J Bioeth. 2020 May;20(4):111-113. doi: 10.1080/15265161.2020.1730490.
9
Research priorities in childhood-onset lupus: results of a multidisciplinary prioritization exercise.儿童发病狼疮的研究重点：多学科优先排序研究的结果。
Pediatr Rheumatol Online J. 2019 Jul 1;17(1):32. doi: 10.1186/s12969-019-0327-4.
10
Transition and transfer of the patient with paediatric-onset lupus: a practical approach for paediatric and adult rheumatology practices.儿童期起病的狼疮患者的过渡与转诊：儿科和成人风湿病诊疗实践的实用方法
Lupus Sci Med. 2018 Aug 13;5(1):e000282. doi: 10.1136/lupus-2018-000282. eCollection 2018.
阿托伐他汀在儿童和青少年系统性红斑狼疮中的应用。
Arthritis Rheum. 2012 Jan;64(1):285-96. doi: 10.1002/art.30645.
4
The developing immune system - from foetus to toddler.发育中的免疫系统——从胎儿到幼儿。
Acta Paediatr. 2012 Feb;101(2):120-7. doi: 10.1111/j.1651-2227.2011.02494.x. Epub 2011 Nov 10.
5
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.早期发病由狼疮的更高遗传风险预测，并与狼疮患者更严重的表型相关。
Ann Rheum Dis. 2011 Jan;70(1):151-6. doi: 10.1136/ard.2010.141697. Epub 2010 Sep 29.
6
Pediatric lupus--are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus?儿科狼疮——与成人狼疮相比，其在临床表现、遗传学、对治疗的反应和损伤累积方面是否存在差异？
Rheum Dis Clin North Am. 2010 Feb;36(1):53-80, vii-viii. doi: 10.1016/j.rdc.2009.12.012.
7
Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case-control study within LUMINA, a multiethnic US cohort (LUMINA LVII).青少年期发病的狼疮会导致病情更具侵袭性且预后更差：美国多民族队列研究LUMINA（LUMINA LVII）中一项巢式匹配病例对照研究的结果
Lupus. 2008 Apr;17(4):314-22. doi: 10.1177/0961203307087875.
8
Association between early onset and organ manifestations of systemic lupus erythematosus (SLE) and a down-regulating promoter polymorphism in the MBL2 gene.系统性红斑狼疮（SLE）的早发与器官表现和甘露糖结合凝集素2（MBL2）基因中一个下调启动子多态性之间的关联。
Clin Immunol. 2007 Dec;125(3):230-6. doi: 10.1016/j.clim.2007.08.020. Epub 2007 Oct 17.
9
Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes.小儿系统性红斑狼疮在三个不同年龄组中的独特临床特征。
Lupus. 2007;16(8):550-5. doi: 10.1177/0961203307080636.
10
Reproductive and menopausal factors and risk of systemic lupus erythematosus in women.女性生殖和绝经因素与系统性红斑狼疮风险
Arthritis Rheum. 2007 Apr;56(4):1251-62. doi: 10.1002/art.22510.