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[新生儿乳糜性腹水:两例报告]

[Neonatal chylous ascites: report of two cases].

作者信息

Liao H B, Hwang R C, Chu D M, Chu M L, Chu C C, Hwang E J

机构信息

Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan, R.O.C.

出版信息

Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1990 Jan-Feb;31(1):47-52.

PMID:2278229
Abstract

Chylous ascites in neonates is an unusual and etiologically poor understood entity. Our first case was a female newborn who suffered from abdominal distension and recurrent vomiting after birth. The history, physical, laboratory, and radiologic evaluations were not diagnostic except the evidence of obvious ascites. Paracentesis was performed and ascitic fluid was obtained. She was later discharged on a strict low-fat medium-chain triglycerides formula. She was found to have continue increase in abdominal girth, poor growth and development, and respiratory distress in which led her to readmission at 8 months of age. Exploratory laparotomy was done in order to rule out an anatomical lesion in which may be obstructing the lymphatic flow; but no such lesion could be found. She expired at 1 year of age with chylothorax, chylopericardium and lobar pneumonia. The second case, a 37-day-old male baby, who was admitted because of right inguinal hernia. Milky ascitic fluid in the abdomen was incidentally found during herniorrhaphy. Analysis of the fluid revealed protein 1,616 mg/dl, glucose 487 mg/dl, and triglyceride 796 mg/dl. Culture of peritoneal fluid grew no bacteria. Other laboratory findings were: serum protein 4.8 mg/dl, and BUN 14 mg/dl. A plain film of abdomen and sonogram showed massive ascites. The infant was then put on Pregestimil with the hope that the medium-chain triglyceride formula would improve his condition. Since then the child's abdominal girth did not increase and he continued to growth and develop normally at 4 months follow up.

摘要

新生儿乳糜性腹水是一种罕见且病因尚不清楚的病症。我们的首例病例是一名女婴,出生后出现腹胀和反复呕吐。除了明显的腹水证据外,病史、体格检查、实验室检查和影像学评估均未明确诊断。进行了腹腔穿刺并获取了腹水。之后她出院并采用严格的低脂中链甘油三酯配方奶喂养。8个月大时,她的腹围持续增加、生长发育不良并出现呼吸窘迫,随后再次入院。为排除可能阻塞淋巴液流动的解剖学病变,进行了剖腹探查术,但未发现此类病变。她在1岁时因乳糜胸、乳糜心包和大叶性肺炎死亡。第二例是一名37天大的男婴,因右侧腹股沟疝入院。在疝修补术中意外发现腹腔内有乳糜样腹水。腹水分析显示蛋白1616mg/dl、葡萄糖487mg/dl、甘油三酯796mg/dl。腹水培养未发现细菌。其他实验室检查结果为:血清蛋白4.8mg/dl、尿素氮14mg/dl。腹部平片和超声检查显示大量腹水。该婴儿随后采用普瑞米尔配方奶喂养,希望中链甘油三酯配方能改善其病情。此后,该患儿的腹围未再增加,在4个月的随访中继续正常生长发育。

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