Epilepsy Unit, Hospital Clinico San Carlos, Madrid, Spain.
Epilepsy Behav. 2012 Aug;24(4):493-6. doi: 10.1016/j.yebeh.2012.06.005. Epub 2012 Jul 10.
To translate and validate into Spanish (Spain) the screening instrument of major depressive episodes (MDEs), Neurological Disorders Depression Inventory in Epilepsy (NDDI-E), in patients with epilepsy.
A total of 121 outpatients, aged 18 years and older, with a diagnosis of epilepsy were included. The diagnosis of a current major depressive episode (MDE) was established with the Mini International Neuropsychiatric Interview (MINI).
A diagnosis of current MDE was established in 20% of the patients with the MINI. Receiver operator characteristics (ROC) analysis showed an area under the curve of 0.89, with an internal consistency of 0.78. At a cutoff score >13, 22% of patients were considered to suffer from MDE with the NDDI-E (sensitivity: 84%; specificity: 78%; positive predictive value: 64.7%; and negative predictive value: 92.2%).
The Spanish-Spain version of the NDDI-E appears to be a good screening instrument to identify MDE.
将癫痫患者的主要抑郁发作（MDE）筛查工具——神经障碍抑郁量表在癫痫中的应用（NDDI-E）翻译成西班牙语（西班牙）并进行验证。
共纳入 121 名年龄在 18 岁及以上的癫痫门诊患者。使用迷你国际神经精神访谈（MINI）对当前重度抑郁发作（MDE）的诊断进行评估。
MINI 诊断为当前 MDE 的患者占 20%。受试者工作特征（ROC）分析显示曲线下面积为 0.89，内部一致性为 0.78。在截断评分＞13 时，NDDI-E 认为 22%的患者患有 MDE（灵敏度：84%；特异性：78%；阳性预测值：64.7%；阴性预测值：92.2%）。
NDDI-E 的西班牙语-西班牙版本似乎是一种很好的 MDE 筛查工具。
