将酶封装在具有小孔径介孔材料的大孔中。
Encapsulation of enzyme in large mesoporous material with small mesoporous windows.
机构信息
CReST Unit, Chemical Engineering Division, National Chemical laboratory, Dr Homi Bhabha Road, Pune, India.
出版信息
Chem Commun (Camb). 2012 Aug 14;48(63):7853-5. doi: 10.1039/c2cc33592a. Epub 2012 Jul 2.
PMID:22786692
Abstract
Trypsin has been encapsulated in the mesopores of a hierarchical mesoporous silica material synthesized via Cu(I) catalyzed azide-alkyne click reaction between azide functionalized large spherical SBA-15 particles and alkyne functionalized mesoporous silica nanoparticles (MSNs). Encapsulated trypsin functions as an efficient biocatalyst and can be recycled several times.
摘要
胰蛋白酶已被包裹在介孔硅材料的介孔中，该介孔硅材料是通过 Cu(I) 催化叠氮化物-炔点击反应，由叠氮功能化的大球形 SBA-15 颗粒和炔功能化的介孔硅纳米颗粒 (MSNs) 合成的。包埋的胰蛋白酶作为一种有效的生物催化剂，可以被多次回收。
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