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耳蜗中的钙信号转导:分子机制与生理病理意义。

Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.

机构信息

Dipartimento di Fisica e Astronomia "G, Galilei", Università di Padova, 35131, Padova, Italy.

出版信息

Cell Commun Signal. 2012 Jul 12;10(1):20. doi: 10.1186/1478-811X-10-20.

Abstract

Calcium ions (Ca2+) regulate numerous and diverse aspects of cochlear and vestibular physiology. This review focuses on the Ca2+ control of mechanotransduction and synaptic transmission in sensory hair cells, as well as on Ca2+ signalling in non-sensory cells of the developing cochlea.

摘要

钙离子(Ca2+)调节耳蜗和前庭生理学的众多不同方面。本综述重点介绍了机械转导和感觉毛细胞突触传递中的 Ca2+ 控制,以及发育中耳蜗非感觉细胞中的 Ca2+ 信号转导。

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