Oneyama Masataka, Sekikawa Koji, Goto Manabu, Kitamura Masaya, Kawahara Yuichi, Ohta Ryo, Takahashi Yasumasa, Hirata Yudai, Nakayama Mikihiro, Shimoda Yota
Dept. of Surgery, Kawasaki Saiwai Hospital, Japan.
Gan To Kagaku Ryoho. 2012 Jul;39(7):1131-3.
A 59-year-old man with type 3 gastric cancer(signet-ring cell carcinoma)underwent simple laparotomy because of peritoneal dissemination.S -1/CDDP was started.Since the icterus of Grade 2 had appeared after 2 courses, S-1 and biweekly paclitaxel combination chemotherapy was started as second-line treatment.Throughout treatment, there was no adverse event, and this regimen was continued for 14 courses(25 months).He died 32 months after his first visit.S -1/PTX may play an important role as second-line chemotherapy for patients with unresectable advanced gastric carcinoma.
一名59岁的3型胃癌(印戒细胞癌)患者因腹膜播散接受了单纯剖腹手术。开始使用S-1/顺铂治疗。在2个疗程后出现2级黄疸,因此开始使用S-1和每两周一次的紫杉醇联合化疗作为二线治疗。在整个治疗过程中,没有出现不良事件,该方案持续了14个疗程(25个月)。他在首次就诊32个月后死亡。S-1/紫杉醇可能作为不可切除的晚期胃癌患者的二线化疗发挥重要作用。