School of Dentistry, Universidade de São Paulo, São Paulo, SP, Brazil.
Braz Oral Res. 2012 Jul-Aug;26(4):348-54. doi: 10.1590/s1806-83242012000400011.
This study analyzed the effects of unilateral detachment of the temporal muscle and coronoidotomy on facial growth in young rats. Thirty one-month-old Wistar rats were distributed into three groups: detachment, coronoidotomy and sham-operated. Under general anesthesia, unilateral detachment of the temporal muscle was performed for the detachment group, unilateral coronoidotomy was performed for the coronoidotomy group, and only surgical access was performed for the sham-operated group. The animals were sacrificed at three months of age. Their soft tissues were removed, and the mandible was disarticulated. Radiographic projections-axial views of the skulls and lateral views of hemimandibles-were taken. Cephalometric evaluations were performed, and the values obtained were submitted to statistical analyses. There was a significant homolateral difference in the length of the premaxilla, height of the mandibular ramus and body, and the length of the mandible in all three groups. However, comparisons among the groups revealed no significant differences between the detachment and coronoidotomy groups for most measurements. It was concluded that both experimental detachment of the temporal muscle and coronoidotomy during the growth period in rats induced asymmetry of the mandible and affected the premaxilla.
本研究分析了在幼年大鼠中单侧颞肌剥离和冠突切开术对面部生长的影响。将 31 月龄的 Wistar 大鼠分为三组：剥离组、冠突切开组和假手术组。在全身麻醉下，对剥离组进行单侧颞肌剥离，对冠突切开组进行单侧冠突切开，对假手术组仅进行手术入路。动物在 3 个月大时被处死。取出其软组织，分离下颌骨。拍摄颅骨轴位放射投影和半下颌侧位放射投影。进行头影测量评估，并对获得的值进行统计分析。所有三组的上颌前段长度、下颌支高度和体部以及下颌骨长度均存在显著的同侧差异。然而，组间比较显示，在大多数测量中，剥离组和冠突切开组之间没有显著差异。结论是，在大鼠生长期进行的实验性颞肌剥离和冠突切开均导致下颌骨不对称，并影响上颌前段。
