Department of Surgery, Køge Hospital, University of Copenhagen, Lykkebækvej 1, 4600 Køge, Denmark.
Hernia. 2013 Jun;17(3):321-7. doi: 10.1007/s10029-012-0956-8. Epub 2012 Jul 12.
Female gender is a risk factor for early pain after several specific surgical procedures but has not been studied in detail after laparoscopic groin hernia repair. The aim of this study was to compare early postoperative pain, discomfort, fatigue, and nausea and vomiting between genders undergoing laparoscopic groin hernia repair.
Prospective consecutive enrollment of women and age-matched (± 1 year) and uni-/bilateral hernia-matched male patients undergoing elective transabdominal preperitoneal hernia repair (TAPP). Patients in the two groups received a similar anesthetic, surgical, and analgesic treatment protocol.
Between August 2009 and August 2010, 25 women and 25 men undergoing elective TAPP were prospectively included in the analysis (n = 50) with no significant difference between groups in psychological status regarding anxiety, depression, and catastrophizing. On day 0, women had significantly more pain during rest (p = 0.015) and coughing (p = 0.012), discomfort (p = 0.001), and fatigue (0.020) compared with men. Additionally, cumulative overall postoperative pain during coughing, discomfort, and fatigue on day 0-3 was significantly higher in women compared with men (all p values < 0.05). Women required significantly more opioids (p = 0.015) and had a significantly higher incidence of vomiting on days 0 and 1 (p = 0.002).
Women experienced more pain, discomfort, and fatigue compared with men after laparoscopic groin hernia repair.
Registration number NCT00962338 ( www.clinicaltrials.gov ).
女性是几种特定手术术后早期疼痛的危险因素,但在腹腔镜腹股沟疝修补术后,这一因素并未得到详细研究。本研究旨在比较女性和男性在接受腹腔镜腹股沟疝修补术后的早期术后疼痛、不适、疲劳和恶心呕吐情况。
前瞻性连续纳入接受择期经腹腹膜前疝修补术(TAPP)的女性和年龄匹配(± 1 年)和单侧/双侧疝匹配的男性患者。两组患者接受类似的麻醉、手术和镇痛治疗方案。
2009 年 8 月至 2010 年 8 月,前瞻性纳入 25 名女性和 25 名男性接受择期 TAPP 患者(n = 50),两组患者在焦虑、抑郁和灾难化方面的心理状态无显著差异。在术后第 0 天,女性在休息时(p = 0.015)和咳嗽时(p = 0.012)、不适(p = 0.001)和疲劳(p = 0.020)方面疼痛明显更严重。此外,与男性相比,女性在术后第 0-3 天咳嗽、不适和疲劳时的累积总术后疼痛明显更高(所有 p 值均<0.05)。女性需要的阿片类药物明显更多(p = 0.015),并且在第 0 天和第 1 天呕吐的发生率明显更高(p = 0.002)。
与男性相比,女性在腹腔镜腹股沟疝修补术后经历了更多的疼痛、不适和疲劳。
注册号 NCT00962338(www.clinicaltrials.gov)。