Vinogradova T M, Sukhova G S, Tumanov A I, Lebedev I A
Biull Eksp Biol Med. 1990 Oct;110(10):356-8.
This study was designed to examine the changes of the isolated frog's heart rate as a function of the time in the two time intervals: 20-95 min and 95-170 min after hearts were prepared. The heart rate decreased in these intervals quite linear but average slope between 20-75 min was significantly steeper than in the time interval 95-170 min. It was shown that the difference in the heart rate response induced by the increasing temperature in intact animals and isolated hearts partly might be explored by this decrease in the isolated frog's heart rate with time.
本研究旨在考察离体青蛙心率随时间的变化，时间范围为心脏制备后的两个时间段：20 - 95分钟和95 - 170分钟。在这些时间段内，心率呈相当线性的下降，但20 - 75分钟之间的平均斜率明显比95 - 170分钟时间段内的更陡。结果表明，完整动物和离体心脏中温度升高引起的心率反应差异，部分原因可能是离体青蛙心率随时间的这种下降。
