Yamanaka Yuki, Ishihama Akira, Yamamoto Kaneyoshi
Department of Frontier Bioscience and Research Center for Micro-Nano Technology, Hosei University, Tokyo, Japan.
Biosci Biotechnol Biochem. 2012;76(6):1236-8. doi: 10.1271/bbb.120041. Epub 2012 Jun 7.
YdeO, an AraC-type transcription factor, is an important regulator in the induction of acid-resistance genes in Escherichia coli. In this study, we found that ydeO expression was induced 20 min after exposure to UV irradiation. This required the evgA and gadE genes in vivo. YdeO, induced by UV, controls the expression of a total of 21 genes. This accompanies SOS response in E. coli.
YdeO是一种AraC型转录因子,是大肠杆菌中诱导耐酸基因的重要调节因子。在本研究中,我们发现暴露于紫外线照射后20分钟,ydeO表达被诱导。这在体内需要evgA和gadE基因。紫外线诱导的YdeO控制总共21个基因的表达。这伴随着大肠杆菌中的SOS反应。