Yanase Yohsuke, Kawaharada Nobuyoshi, Maeda Toshiyuki, Koyanagi Tetsuya, Ito Toshiro, Kurimoto Yoshihiko, Higami Tetsuya
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University of Medicine, Sapporo, Hokkaido, Japan.
Ann Thorac Cardiovasc Surg. 2012;18(3):271-4. doi: 10.5761/atcs.cr.11.01741.
Delayed neurologic deficits, paraplegia and paraparesis, are devastating complications after repair of a descending thoracic and thoracoabdominal aortic aneurysm (TAAA). A treatment protocol has not been established, although strategies such as cerebrospinal fluid (CSF) drainage, maintaining blood pressure and medication have been described. Cerebrospinal drain status /oxygen delivery/patient status (COPS) therapy for delayed neurological deficit can improve spinal cord ischemia through reducing intraspinal pressure, improving oxygen delivery and maintaining high blood pressure. We describe one patient (Case 1), in whom descending thoracic and abdominal aortic aneurysms were treated by endovascular aortic repair, and another (Case 2) with Crawford type II TAAA, who developed delayed neurological deficits that were treated with immediate COPS therapy (Modified Tarlov scale; Case 1, improved from 2 to 4; Case 2, from 0 to 4). These findings indicate the benefit of COPS for treating delayed neurological deficits after descending thoracic and TAAA.
延迟性神经功能缺损、截瘫和轻截瘫是降主动脉和胸腹主动脉瘤(TAAA)修复术后的灾难性并发症。尽管已经描述了诸如脑脊液(CSF)引流、维持血压和药物治疗等策略,但尚未建立治疗方案。用于治疗延迟性神经功能缺损的脑脊液引流状态/氧输送/患者状态(COPS)疗法可通过降低椎管内压力、改善氧输送和维持高血压来改善脊髓缺血。我们描述了一例(病例1)降主动脉和腹主动脉瘤通过血管腔内主动脉修复术治疗的患者,以及另一例(病例2)患有克劳福德II型TAAA的患者,该患者出现了延迟性神经功能缺损,并立即接受了COPS疗法治疗(改良塔洛夫量表;病例1从2级改善到4级;病例2从0级改善到4级)。这些发现表明COPS疗法在治疗降主动脉和TAAA术后延迟性神经功能缺损方面的益处。