Saini Rajesh, Bajpai Jaya, Bajpai Anil K
Department of Chemistry, Bose Memorial Research Laboratory, Government Autonomous Science College, Jabalpur, MP, India.
Methods Mol Biol. 2012;906:321-8. doi: 10.1007/978-1-61779-953-2_26.
The performance of polymeric nanomaterials relies greatly upon their properties which are intimately related to the methods of fabrication of the materials. Among various synthetic polymers, the polymers of 2-hydroxyetyhyl methacrylate (PHEMA) maintain a prime position in biomedical field due to their useful physicochemical properties and suitability for controlled drug delivery applications. Here we focus on three methods of preparation of PHEMA nanoparticles, by suspension polymerization, emulsion polymerization and dispersion polymerization without the use of any surfactants.
聚合物纳米材料的性能在很大程度上取决于其性质，而这些性质与材料的制备方法密切相关。在各种合成聚合物中，聚甲基丙烯酸2-羟乙酯（PHEMA）聚合物因其有用的物理化学性质以及适用于控释药物应用，在生物医学领域占据重要地位。在此，我们重点介绍三种制备PHEMA纳米颗粒的方法，即悬浮聚合、乳液聚合和不使用任何表面活性剂的分散聚合。
