Bajaj N, Mullen D, Wylie S
Department of General Adult Psychiatry, Falkirk Royal Infirmary, UK.
BMJ Case Rep. 2010 Nov 3;2010:bcr0220102780. doi: 10.1136/bcr.02.2010.2780.
'Legal highs' are recreational drugs sold over the internet and the so-called 'head shops' all over the UK. They are freely available to buy and use as they are not covered by the Misuse of Drugs Act 1971. Mephedrone (4-methylmethcathinone) was sold as a 'legal high' until 17 April 2010 when it was made a class B drug under the Misuse of Drugs Act 1971. Numerous deaths and self-harm has been associated with mephedrone use. Effects of mephedrone are reported to be empathogenic similar to 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and stimulant properties similar to cocaine. Not much is known of the effects of mephedrone on mental health. We present a case of dependence and psychosis in a patient using mephedrone (4-methylmethcathinone). The patient needed inpatient hospital care, was treated with antipsychotic olanzapine and recovered well.
“合法兴奋剂”是在互联网上以及遍布英国的所谓“烟具店”出售的消遣性毒品。它们可以自由买卖和使用，因为不受1971年《滥用毒品法》的管制。甲氧麻黄酮（4-甲基甲卡西酮）在2010年4月17日之前作为“合法兴奋剂”出售，之后根据1971年《滥用毒品法》被列为B类毒品。大量死亡和自残事件与甲氧麻黄酮的使用有关。据报道，甲氧麻黄酮的效果与3,4-亚甲基二氧甲基苯丙胺（摇头丸）类似，具有致共情作用，同时具有与可卡因类似的兴奋特性。关于甲氧麻黄酮对心理健康的影响，人们了解得并不多。我们报告了一例使用甲氧麻黄酮（4-甲基甲卡西酮）的患者出现成瘾和精神病症状的病例。该患者需要住院治疗，接受了抗精神病药物奥氮平治疗，恢复良好。
