在灵长类动物产前发育过程中，具有轴突侧支投射到两侧大脑半球的视觉皮层神经元的发生率。

Incidence of visual cortical neurons which have axon collaterals projecting to both cerebral hemispheres during prenatal primate development.

作者信息

Meissirel C, Dehay C, Berland M, Kennedy H

机构信息

Vision et Motricité, INSERM U94, Bron, France.

出版信息

Brain Res Dev Brain Res. 1990 Oct 1;56(1):123-6. doi: 10.1016/0165-3806(90)90170-4.

DOI:10.1016/0165-3806(90)90170-4

PMID:2279323

Abstract

Fast blue was injected massively in extrastriate cortex of one hemisphere Diamidino yellow in area 17 of the other hemisphere, in adult and prenatal cynomolgus monkeys. After a suitable survival period the brains were processed for fluorescent dyes. Counts were made of the total number of labeled neurons and of those neurons which were labeled by both dyes and which project therefore to both hemispheres by means of bifurcating axon collaterals. At 122 and 135 days after conception (E122 and E135), shortly after cortico-cortical pathways are established, double-labeled neurons constituted 0.45% and 0.46% of the total population of labeled neurons in area V2. In V2 in the adult the range of values of double-labeled neurons was 0.03-0.08%.

摘要

在成年和产前食蟹猴中，将大量快蓝注射到一个半球的纹外皮层，将双脒基黄注射到另一个半球的17区。经过适当的存活期后，对大脑进行荧光染料处理。统计标记神经元的总数，以及那些被两种染料标记并因此通过分叉轴突侧支投射到两个半球的神经元数量。在受孕后122天和135天（E122和E135），即皮质-皮质通路建立后不久，V2区双标记神经元占标记神经元总数的0.45%和0.46%。在成年猴的V2区，双标记神经元的数值范围为0.03-0.08%。