Girgis N I, Farid Z, Mansour M, Yassin H, Kilpatrick M E
Naval Medical Research Unit 3, Abbassia Fever Hospital, Cairo, Egypt.
East Afr Med J. 1990 Jun;67(6):404-6.
The bromine partition test was successfully used to differentiate cases of proven tuberculous meningitis from patients with aseptic and non-tuberculous meningitis. Forty patients, 22 males and 18 females aged 5 to 30 years (mean 13.5 +/- 6.2), were included in the study. Nineteen patients were confirmed to have tuberculous meningitis, 12 had aseptic meningitis, and 9 bacterial meningitis. All patients received 0.6 mci/kg of bromine 82 administered through a nasogastric tube as ammonium bromide dissolved in 5 ml of isotonic sodium chloride. The serum to CSF bromine ratio was then calculated 48 hours after the dose. The test was then repeated 8 days later in patients with bacterial meningitis and 8, 90, and 180 day later in patients with tuberculous meningitis. The test was very useful in quickly differentiating cases of aseptic from bacterial and tuberculous meningitis and was also a useful prognosticator in patients with severe tuberculous meningitis.
溴分区试验成功用于区分确诊的结核性脑膜炎病例与无菌性和非结核性脑膜炎患者。本研究纳入了40例患者，其中男性22例，女性18例，年龄5至30岁（平均13.5±6.2岁）。19例确诊为结核性脑膜炎，12例为无菌性脑膜炎，9例为细菌性脑膜炎。所有患者通过鼻胃管接受0.6 mci/kg的溴82，以溶解于5 ml等渗氯化钠中的溴化铵形式给药。给药48小时后计算血清与脑脊液的溴比值。细菌性脑膜炎患者在8天后重复该试验，结核性脑膜炎患者在8天、90天和180天后重复该试验。该试验在快速区分无菌性脑膜炎与细菌性和结核性脑膜炎病例方面非常有用，并且在重症结核性脑膜炎患者中也是一个有用的预后指标。
