Blennow G, Heijbel J, Sandstedt P, Tonnby B
Department of Paediatrics, University Hospital, Lund, Sweden.
Epilepsia. 1990;31 Suppl 4:S50-3. doi: 10.1111/j.1528-1157.1990.tb05871.x.
Cognitive function is frequently impaired in children with epilepsy, compared with age-matched controls. It can be hard to evaluate the significance of various contributory factors. The effects of antiepileptic drugs may be studied in children who have outgrown their epilepsy but are still being treated. A multicenter study to assess various aspects of cognitive function in children with different forms of epilepsy, both during and after treatment with antiepileptic drugs, is currently under way. Definitive results are not yet available; interim analysis of the findings suggests that short-term memory is decreased in all subgroups of children being treated for epilepsy, compared to controls.
与年龄匹配的对照组相比，癫痫患儿的认知功能常常受损。很难评估各种促成因素的重要性。抗癫痫药物的影响可以在癫痫已缓解但仍在接受治疗的儿童中进行研究。目前正在进行一项多中心研究，以评估不同类型癫痫儿童在抗癫痫药物治疗期间及治疗后的认知功能各个方面。确切结果尚未可得；对研究结果的中期分析表明，与对照组相比，正在接受癫痫治疗的所有儿童亚组的短期记忆均有所下降。
