Department of Otolaryngology-Head and Neck Surgery, Cukurova University School of Medicine, Adana, Turkey.
J Craniomaxillofac Surg. 2013 Mar;41(2):140-3. doi: 10.1016/j.jcms.2012.06.006. Epub 2012 Jul 12.
Extramedullary plasmacytomas are localized tumours formed of monoclonal plasma cells in an extra-skeletal area. They constitute approximately 3% of all neoplasms originating from plasma cells. They generally display a destructive course. When the literature in English was reviewed, only 19 cases with the primary disease localized in the sphenoid sinus were found. We present the case of a 50-year-old male patient who presented with gradually increasing visual loss over 6 weeks, whose radiological tests revealed a formation of mass in the sphenoid sinus pressing against the optic nerve and internal carotid artery. A biopsy obtained by endoscopic sinus surgery was reported to be a plasmacytoma. A diagnosis of extramedullary plasmacytoma was made after investigations for other neoplastic plasma cell conditions proved negative. Extramedullary plasmacytomas were assessed by reviewing the literature.
髓外浆细胞瘤是由骨骼外部位的单克隆浆细胞形成的局限性肿瘤。它们约占所有源自浆细胞的肿瘤的 3%。它们通常表现为侵袭性病程。当我们查阅英文文献时，仅发现 19 例原发于蝶窦的病例。我们报告了 1 例 50 岁男性患者，他在 6 周内逐渐出现视力下降，影像学检查显示蝶窦内有肿块，压迫视神经和颈内动脉。通过鼻内镜手术获得的活检报告为浆细胞瘤。在排除其他浆细胞肿瘤的情况下，诊断为髓外浆细胞瘤。通过复习文献评估了髓外浆细胞瘤。
