Laboratory of Neurophysiology and Movement Biomechanics, Universite Libre de Bruxelles, Brussels, Belgium.
Comput Biol Med. 2012 Aug;42(8):857-62. doi: 10.1016/j.compbiomed.2012.06.009. Epub 2012 Jul 15.
In this paper we detail a phase lagging model of brain response to external stimuli. The model is derived using the basic laws of physics like conservation of energy law. This model eliminates the paradox of instantaneous propagation of the action potential in the brain. The solution of this model is then presented. The model is further applied in the case of a single neuron and is verified by simulating a single action potential. The results of this modeling are useful not only for the fundamental understanding of single action potential generation, but also they can be applied in case of neuronal interactions, where the results can be verified against the real EEG signal.
本文详细介绍了一种用于描述大脑对外界刺激产生反应的时滞模型。该模型基于能量守恒定律等基本物理定律推导得出。该模型消除了动作电位在大脑中瞬时传播的悖论。本文随后给出了该模型的解。该模型进一步应用于单个神经元的情况，并通过模拟单个动作电位进行了验证。该模型的结果不仅有助于深入理解单个动作电位的产生，还可应用于神经元相互作用的情况，在这种情况下，可以根据实际的 EEG 信号对结果进行验证。
