Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Crit Rev Oncol Hematol. 2012 Nov;84(2):252-60. doi: 10.1016/j.critrevonc.2012.06.005. Epub 2012 Jul 12.
Breast cancer is the most common malignancy amongst women in the developed world. For patients with hormone-sensitive breast cancer eligible for adjuvant hormonal therapy, it is important to know if the ovaries are (still) functional or not. Indeed, the choice for a specific adjuvant hormonal treatment depends on the menopausal status of an individual woman. The currently available measures to determine the menopausal status are conflicting. Until better measures become available, we propose a practical guideline enabling an optimal choice of adjuvant hormonal therapy for women with a hormone receptor positive breast cancer taking into account uncertainties about their menopausal status.
在发达国家，乳腺癌是女性最常见的恶性肿瘤。对于有资格接受辅助激素治疗的激素敏感型乳腺癌患者，了解卵巢是否（仍然）具有功能非常重要。实际上，特定辅助激素治疗的选择取决于个体女性的绝经状态。目前用于确定绝经状态的方法存在矛盾。在更好的方法出现之前，我们提出了一个实用的指南，考虑到对激素受体阳性乳腺癌女性绝经状态的不确定性，使她们能够为自己选择最佳的辅助激素治疗方案。
