Department of Cardiac Surgery, University of Leipzig Heart Center, Leipzig, Germany.
J Thorac Cardiovasc Surg. 2013 Jul;146(1):109-13. doi: 10.1016/j.jtcvs.2012.06.044. Epub 2012 Jul 15.
Mitral valve repair for anterior mitral leaflet prolapse is technically challenging. We report here our experience with minimally invasive anterior mitral leaflet repair.
Our institutional database for minimally invasive mitral valve surgery was screened for patients with mitral regurgitation caused by isolated prolapse of the anterior mitral leaflet. Patient characteristics, intraoperative data, and short- and long-term outcomes are analyzed and reported.
A total of 180 patients presented with mitral regurgitation caused by isolated anterior mitral leaflet prolapse. All patients underwent minimally invasive surgery at our institution between 1999 and 2010. Mitral valve repair was performed in 170 cases (94.4%), and these patients form the focus of this study. The mean age of the patients was 59.7 ± 14.8, and their mean log EuroSCORE was 4.9 ± 5.1. Mean aortic crossclamp time (cardiopulmonary bypass time) was 82 ± 25 minutes (130 ± 40 minutes). Mitral valve repair techniques were neochordal replacement with the loop technique in 68.2% of patients, chordal transfer in 14.7%, anterior mitral leaflet resection in 7.1%, and edge-to-edge repair in 5.9%. Thirty-day mortality was 1.8%. Kaplan-Meier estimates showed 86.7% ± 3.2% survival and 95.7% ± 1.6% freedom from mitral valve reoperation at 5 years.
This large series demonstrates good results for anterior mitral leaflet repair with the minimally invasive approach.
二尖瓣前叶脱垂的二尖瓣修复技术具有挑战性。我们在此报告我们应用微创二尖瓣前叶修复的经验。
我们的微创二尖瓣手术机构数据库筛选出因孤立性二尖瓣前叶脱垂引起的二尖瓣反流患者。分析并报告患者特征、术中数据以及短期和长期结果。
共有 180 例患者因孤立性二尖瓣前叶脱垂导致二尖瓣反流。所有患者均于 1999 年至 2010 年在我院接受微创外科手术。170 例(94.4%)患者接受二尖瓣修复,这些患者是本研究的重点。患者的平均年龄为 59.7±14.8 岁,平均 log EuroSCORE 为 4.9±5.1。平均主动脉阻断时间(体外循环时间)为 82±25 分钟(130±40 分钟)。二尖瓣修复技术包括:68.2%患者采用 Loop 技术行人工腱索置换,14.7%患者采用腱索转移,7.1%患者行前瓣叶切除术,5.9%患者行边缘对边缘修复术。30 天死亡率为 1.8%。Kaplan-Meier 估计显示,5 年时的存活率为 86.7%±3.2%,二尖瓣再手术的无失败率为 95.7%±1.6%。
这项大型系列研究表明,微创方法治疗二尖瓣前叶脱垂的效果良好。