Westgard J O, Cembrowski G S
Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison 53703.
Eur J Haematol Suppl. 1990;53:14-8. doi: 10.1111/j.1600-0609.1990.tb01521.x.
An approach is described for selecting QC procedures based on goals for analytical quality, the performance characteristics of the measurement procedure (imprecision, bias, frequency of errors), and the performance characteristics of the control procedure (probabilities for error detection and false rejection). Performance characteristics of stable sample QC procedures and patient data QC procedures (retained patient specimens, Bull's single-rule algorithm, Bull's multi-rule algorithm) are compared to determine when to apply these different QC procedures to multichannel hematology analysers. Precise, stable methods may be controlled using Bull's single-rule algorithm; less precise, less stable methods require Bull's multi-rule algorithm, retained patient specimens, or stable sample QC procedures; imprecise and unstable methods are best controlled using stable sample QC procedures. "Multi-stage" designs may employ stable samples for "startup" testing, retained patient specimens for short term monitoring, and Bull's single-rule algorithm for long term monitoring.
本文描述了一种基于分析质量目标、测量程序的性能特征（不精密度、偏差、误差频率）以及控制程序的性能特征（误差检测和假拒收概率）来选择质量控制程序的方法。比较了稳定样本质量控制程序和患者数据质量控制程序（留存患者标本、布尔单规则算法、布尔多规则算法）的性能特征，以确定何时将这些不同的质量控制程序应用于多通道血液学分析仪。精确、稳定的方法可使用布尔单规则算法进行控制；不太精确、不太稳定的方法需要布尔多规则算法、留存患者标本或稳定样本质量控制程序；不精确且不稳定的方法最好使用稳定样本质量控制程序进行控制。“多阶段”设计可采用稳定样本进行“启动”测试，留存患者标本进行短期监测，布尔单规则算法进行长期监测。
